IFNB1 antibody (AA 101-187)

Catalog No. ABIN728158

This Rabbit Polyclonal antibody specifically detects IFNB1 in ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human and Ratand has been mentioned in 1 publication.

Quick Overview for IFNB1 antibody (AA 101-187) (ABIN728158)

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IFNB1 Antibody

Binding Specificity: AA 101-187

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFN-beta

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IFNB1 antibody (ABIN728158)

Quek, Luff, Cheung, Kozlov, Gatei, Lee, Bellingham, Noakes, Lim, Barnett, Dingwall, Wolvetang, Mashimo, Roberts, Lavin: "Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage." in: Journal of leukocyte biology, Vol. 101, Issue 4, pp. 927-947, (2016) (PubMed).

Target Details for IFNB1

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Alternative Name: IFN-beta

Background:

Synonyms: IFB, IFF, IFNB, IFN-beta, Interferon beta, Fibroblast interferon, IFNB1

Background: Has antiviral, antibacterial and anticancer activities.

Gene ID: 3456

UniProt: P01574

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome