Cadherin 5 antibody (CDH5) (AA 621-660)

Details for Product anti-CDH5 Antibody No. ABIN729343, Supplier: Log in to see
Antigen
  • 7B4
  • AA408225
  • Cd144
  • VE-Cad
  • VECD
  • VEcad
  • Vec
  • wu:fc88a07
  • CD144
  • cadherin-5
  • cadherin 5
  • CDH5
  • Cdh5
  • cdh5
Alternatives
anti-Human Cadherin 5 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 621-660
23
21
19
15
13
12
9
8
6
6
6
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
278
175
69
5
3
2
2
2
1
1
1
Host
Rabbit
157
152
86
1
Clonality
Polyclonal
Conjugate
This Cadherin 5 antibody is un-conjugated
28
20
19
17
16
9
9
8
6
6
5
5
5
5
5
5
5
4
4
4
4
4
3
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
230
205
129
115
48
40
39
14
13
13
12
11
10
8
7
7
6
6
4
3
3
3
3
3
2
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide derived from mouse vascular endothelial cadherin
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others Cadherin 5 products on genomics-online (e.g. as negative or positive controls)
Alternative Name VE Cadherin (CDH5 Antibody Abstract)
Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Subcellular location: Cytoplasm

Synonyms: 7B4, Vec, VECD, Cd144, VEcad, VE-Cad, AA48225, Cadherin-5, Vascular endothelial cadherin, VE-cadherin, Cdh5

Gene ID 12562
UniProt P55284
Pathways Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-CD144/V...
Immunofluorescence (IF) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Images provided by Science Direct, badge number 029590: Formalin-fixed and frozen-OCT...
Western Blotting (WB) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) A549 lyates probed with Rabbit Anti-VE Cadherin Polyclonal Antibody, Unconjugated at...
Western Blotting (WB) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Mouse heart lysates probed with VE Cadherin Polyclonal Antibody, unconjugated at 1:3...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Image provided by One World Lab validation program. HEK293 cells probed with Rabbit A...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Image provided by One World Lab validation program. A549 cells probed with Rabbit Ant...
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