IKK alpha antibody (pSer176)

Catalog No. ABIN7674378

The Rabbit Polyclonal anti-IKK alpha antibody is suitable to detect IKK alpha in samples from Human and Mouse. It has been validated for WB.

Quick Overview for IKK alpha antibody (pSer176) (ABIN7674378)

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKK alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IKK alpha Antibody

Binding Specificity: pSer176

Purpose: Phospho-IKKα/β antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: A synthetic phosphorylated peptide around S176 of human IKK-alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.06 % PC300 and 50 % glycerol pH 7.3,

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Alternative Name: IKKalpha

Background: Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase)|Conserved helix-loop-helix ubiquitous kinase|I-kappa-B kinase 1 (IKK-1, IKK1)|Nuclear factor NF-kappa-B inhibitor kinase alpha (NFKBIKA)|Transcription factor 16 (TCF-16)|CHUK|IKKA|TCF16

Molecular Weight: 85 kDa

UniProt: O15111, O14920

Pathways: PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins