HGF antibody (AA 201-300)

Catalog No. ABIN736551

Cited in 6+ publications. The Rabbit Polyclonal anti-HGF antibody (ABIN736551) specifically detects HGF in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). The antibody is reactive with Human, Rat, Mouse and Sheep samples.

Quick Overview for HGF antibody (AA 201-300) (ABIN736551)

Target: HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Reactivity: Human, Rat, Mouse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HGF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HGF Antibody

Binding Specificity: AA 201-300

Cross-Reactivity: Human, Mouse, Rat, Sheep

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HGF alpha

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-HGF antibody (ABIN736551)

Zhi, Li, Lv, Feng, Yang, Xue, Zhao, Zhang, Wu, Jv, Jia: "Effects of PHA-665752 and vemurafenib combination treatment on in vitro and murine xenograft growth of human colorectal cancer cells with BRAFV600E mutations." in: Oncology letters, Vol. 15, Issue 3, pp. 3904-3910, (2018) (PubMed).

Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).

Wu, Guo, Su, Wu, Li: "Biocharacterization of Heat Shock Protein 90 in Acetaminophen-Treated Livers Without Conspicuous Drug Induced Liver Injury." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 43, Issue 4, pp. 1562-1570, (2017) (PubMed).

Yu, He, Jiang, He, Fan, Wang, Geng, Dong: "Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors." in: Acta histochemica, (2015) (PubMed).

Li, Zhang, Zhao, Shi, Yao, Zhang, Guo, Liu: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." in: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).

Bi, Hou, Yang, Zhao, Li, Zhao, Zhang: "Effect of bone marrow stem cell mobilisation on the expression levels of cellular growth factors in a rat model of acute tubular necrosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 618-624, (2015) (PubMed).

Target Details for HGF

Target: HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Alternative Name: HGF

Background:

Synonyms: SF, HGFB, HPTA, F-TCF, DFNB39, Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, HGF

Background: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

Gene ID: 3082

UniProt: P14210

Pathways: RTK Signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor