Recombinant Retinoblastoma 1 antibody (pSer780)

Catalog No. ABIN7800183

The Rabbit Monoclonal anti-Retinoblastoma 1 antibody is suitable to detect Retinoblastoma 1 in samples from Human. It has been validated for WB.

Quick Overview for Recombinant Retinoblastoma 1 antibody (pSer780) (ABIN7800183)

Target: Retinoblastoma 1 (RB1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Retinoblastoma 1 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: KD Validated

Clone: 25GB5925

Product Details anti-Retinoblastoma 1 Antibody

Binding Specificity: pSer780

Expression System: HEK-293 Cells

Purpose: KD-Validated Phospho-Rb (S780) Recombinant Rabbit mAb

Cross-Reactivity: Mouse, Rat

Purification: Affinity Purified

Immunogen: A synthesized peptide derived from human Phospho-Rb (S780)

Isotype: IgG

Application Details

Application Notes: Western Blotting (WB): 1:1,000-1:5,000

Comment:

We assess the antibodies’ specificity and selectivity using knockdown techniques. Our validation approach is straightforward: if an antibody identifies a signal in wild-type (WT) cells, but this signal is absent or noticeably reduced in gene-silenced (KD) cells, we consider the antibody to be highly specific.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS (pH 7.4) containing 50% glycerol and 0.02% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C for one year.

Expiry Date: 12 months

Target Details for Retinoblastoma 1

Target: Retinoblastoma 1 (RB1)

Alternative Name: Rb

Molecular Weight: 106 kDa

Gene ID: 5925

UniProt: P06400

Pathways: Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy