Recombinant PIK3CA antibody

Catalog No. ABIN7828457

The Rabbit Monoclonal anti-PIK3CA antibody is suitable to detect PIK3CA in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for Recombinant PIK3CA antibody (ABIN7828457)

Target: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PIK3CA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A333

Product Details anti-PIK3CA Antibody

Purpose: Recombinant PI3 Kinase p110 alpha Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PI3 Kinase p110 alpha fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PIK3CA

Target: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Alternative Name: PI3 Kinase p110 alpha

Background: CWS,PIK3CA,CLOVE,CWS5,MCAP,MCM,MCMTC,PI3K,PI3K-alpha,5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha,5-bisphosphate 3-kinase catalytic subunit alpha isoform,caPI3K,MGC142161,MGC142163,p110 alpha,p110alpha,Phosphatidylinositol 3 kinase catalytic 110 KD alpha,Phosphatidylinositol 3 kinase catalytic alpha polypeptide,Phosphatidylinositol 4,Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha,Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform,Phosphatidylinositol-4,Phosphoinositide 3 kinase catalytic alpha polypeptide,Phosphoinositide 3-kinase alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,PI3 kinase p110 subunit alpha,PI3Kalpha,PI3KC A,PI3-kinase subunit alpha,PIK3C A,PK3CA,PtdIns 3 kinase p110,PtdIns-3-kinase subunit alpha,PtdIns-3-kinase subunit p110-alpha,Serine/threonine protein kinase PIK3CA,Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 110 kDa

Observed MW: 120 kDa The actual band is not consistent with the expectation.

UniProt: P42336

Pathways: PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling