Recombinant PDK2 antibody

Catalog No. ABIN7828509

The Rabbit Monoclonal anti-PDK2 antibody (Clone A433) (ABIN7828509) specifically detects PDK2 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant PDK2 antibody (ABIN7828509)

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDK2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A433

Product Details anti-PDK2 Antibody

Purpose: Recombinant PDK2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PDK2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PDK2

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Alternative Name: PDK2

Background: PDK,PDHK,Pyruvate dehydrogenase kinase isoform,Pyruvate dehydrogenase lipoamide kinase isozyme,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme,isozyme,PDK2,PDHK2,PDKII,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2,isozyme 2,mitochondrial,Pyruvate dehydrogenase kinase,Pyruvate dehydrogenase kinase isoform 2,Pyruvate dehydrogenase lipoamide kinase isozyme 2,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 46 kDa

Observed MW: 46 kDa

UniProt: Q15119

Pathways: PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect