Recombinant PDK4 antibody

Catalog No. ABIN7828510

This Rabbit Monoclonal antibody specifically detects PDK4 in WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Recombinant PDK4 antibody (ABIN7828510)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Antibody Type: Recombinant Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDK4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A735

Product Details anti-PDK4 Antibody

Purpose: Recombinant PDK4 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Alternative Name: PDK4

Background: PDK,PDHK,Pyruvate dehydrogenase lipoamide kinase isozyme,PDK4 PDHK,PDK4,FLJ40832,mitochondrial,Pyruvate dehydrogenase lipoamide kinase isozyme 4,PDK4 PDHK4,PDHK4,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4,Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase 4,Pyruvate dehydrogenase kinase isoenzyme 4,Pyruvate dehydrogenase kinase isoform 4,Pyruvate dehydrogenase kinase isozyme 4,Pyruvate dehydrogenase kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis. Enhanced PDK4 expression may be caused by the increase in free fatty acids that occurs during starvation. Free fatty acids can activate peroxisome proliferator-activated receptor α (PPARα), and activation of PPARα can promote PDK4 expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 46 kDa

Observed MW: 44 kDa The actual band is not consistent with the expectation.

UniProt: Q16654

Pathways: PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect