Caspase 8 antibody (C-Term)

Catalog No. ABIN7835349

This Mouse Monoclonal antibody specifically detects Caspase 8 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (C-Term) (ABIN7835349)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Grade: KO Validated, KD Validated

Product Details anti-Caspase 8 Antibody

Binding Specificity: C-Term

Purpose: Mouse monoclonal antibody to Caspase 8

Specificity: Recognizes endogenous levels of Caspase 8 protein.

Purification: This antibody is purified through a protein G column.

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Caspase 8. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), FC (1/10 - 1/50)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8

Background: MCH5, Caspase-8, CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, MACH

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades