Recombinant RIPK1 antibody (Cleaved-Asp324)

Catalog No. ABIN7847764

The Rabbit Monoclonal anti-RIPK1 antibody is suitable to detect RIPK1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Recombinant RIPK1 antibody (Cleaved-Asp324) (ABIN7847764)

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RIPK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIPK1 Antibody

Binding Specificity: Cleaved-Asp324

Expression System: HEK-293 Cells

Purpose: Recombinant rabbit monoclonal antibody to RIPK1 (Cleaved-D324)

Specificity: Recognizes endogenous levels of RIPK1 (Cleaved-D324) protein

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence human Cleaved-RIPK1. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/2000)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS, pH 7.4, containing 50 % glycerol, 0.05 % BSA and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Alternative Name: RIPK1

Background: RIP, RIP1, Receptor-interacting serine/threonine-protein kinase 1, Cell death protein RIP, Receptor-interacting protein 1, RIP-1, Serine/threonine-protein kinase RIP

Gene ID: 8737, 19766

UniProt: Q13546

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway