FOXO3 antibody (AA 312-537)
Quick Overview for FOXO3 antibody (AA 312-537) (ABIN7873851)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 312-537
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Purpose
- FKHRL1 Antibody / FOXO3A
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Purification
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids R312-Q537) was used as the immunogen for the FKHRL1 antibody.
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Isotype
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 Reactivity: Human WB, IF, IHC (p), ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Sheep, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 Reactivity: Human, Rat WB, IHC, IF, ICC, FACS Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivity: Human ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Monoclonal 1E2 unconjugated Recombinant Antibody
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Application Notes
- Optimal dilution of the FKHRL1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the FKHRL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FKHRL1
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Background
- Forkhead box O3, also known as FKHRL1 (Forkhead in rhabdomyosarcoma-like 1) or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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