GCKR antibody (AA 8-569)

Catalog No. ABIN7876839

The Rabbit Polyclonal anti-GCKR antibody is suitable to detect GCKR in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for GCKR antibody (AA 8-569) (ABIN7876839)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCKR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GCKR Antibody

Binding Specificity: AA 8-569

Purpose: Glucokinase Regulator Antibody / GCKR

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids Q8-Q569) was used as the immunogen for the Glucokinase Regulator antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Glucokinase Regulator antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Glucokinase Regulator antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Alternative Name: Glucokinase Regulator

Background: The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus