Recombinant CD45RA antibody (full length)

Catalog No. ABIN7877898

The Rabbit Monoclonal anti-CD45RA antibody is suitable to detect CD45RA in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CD45RA antibody (full length) (ABIN7877898)

Target: CD45RA

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD45RA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PTPRC-7019R

Product Details anti-CD45RA Antibody

Binding Specificity: full length

Purpose: Recombinant CD45RA Antibody (Leukocyte marker)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human PTPRC protein was used as the immunogen for the recombinant CD45RA antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant CD45RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant CD45RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD45RA

Target: CD45RA

Alternative Name: CD45RA

Background: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

UniProt: P08575