Recombinant CD45RA antibody (full length)

Catalog No. ABIN7877903

This Rabbit Monoclonal antibody specifically detects CD45RA in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CD45RA antibody (full length) (ABIN7877903)

Target: CD45RA

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD45RA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: PTPRC-8699R

Product Details anti-CD45RA Antibody

Binding Specificity: full length

Purpose: CD45RA Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human PTPRC protein was used as the immunogen for the CD45RA antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the CD45RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CD45RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD45RA

Target: CD45RA

Alternative Name: CD45RA

Background: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

UniProt: P08575