Recombinant IGF1 antibody (full length)

Catalog No. ABIN7878414

The Rabbit Monoclonal anti-IGF1 antibody is suitable to detect IGF1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Recombinant IGF1 antibody (full length) (ABIN7878414)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IGF1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: IGF1-2872R

Product Details anti-IGF1 Antibody

Binding Specificity: full length

Purpose: Recombinant Insulin-like Growth Factor 1 Antibody / IGF-1

Purification: Protein A affinity chromatography

Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant Insulin-like Growth Factor 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant Insulin-like Growth Factor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Insulin-like Growth Factor 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Alternative Name: Insulin-like Growth Factor 1

Background: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

UniProt: P05019

Pathways: RTK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation