Recombinant Caspase 8 antibody (cleaved, Large Subunit)

Catalog No. ABIN7879472

This Rabbit Monoclonal antibody specifically detects Caspase 8 in WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant Caspase 8 antibody (cleaved, Large Subunit) (ABIN7879472)

Target: Caspase 8 (CASP8)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RM442

Product Details anti-Caspase 8 Antibody

Binding Specificity: cleaved, Large Subunit

Purpose: Cleaved Caspase 8 Antibody

Purification: Protein A purified from animal origin-free supernatant

Immunogen: A peptide encompassing the pro-domain-large subunit cleavage site of Caspase 8 was used as the immunogen for the Cleaved Caspase 8 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant Cleaved Caspase 8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 50 % glycerol, 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the recombinant Cleaved Caspase 8 antibody at -20oC.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: Caspase 8

Background: This antibody reacts specifically to the cleavage site on the pro domain created after being cleaved from the large subunit of Caspase 8.

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades