XRCC6 antibody

Catalog No. ABIN7882711

The Rabbit Monoclonal anti-XRCC6 antibody is suitable to detect XRCC6 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for XRCC6 antibody (ABIN7882711)

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This XRCC6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AAIG-24

Product Details anti-XRCC6 Antibody

Purpose: Ku70 Antibody / XRCC6

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Ku70 / XRCC6 was used as the immunogen for the Ku70 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Ku70 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Ku70 antibody at -20oC.

Target Details for XRCC6

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Alternative Name: Ku70

Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [RefSeq]

UniProt: P12956

Pathways: DNA Damage Repair