FOXO3 antibody (AA 312-537) (Fluoro550)
Quick Overview for FOXO3 antibody (AA 312-537) (Fluoro550) (ABIN7991538)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 312-537
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Purpose
- Anti-FOXO3A/FOXO3 Antibody Fluoro550 Conjugated
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human FOXO3A/FOXO3 recombinant protein (Position: R312-Q537).
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Isotype
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 Reactivity: Human WB, IF, ICC, IHC (p), IP Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivity: Human ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Monoclonal 1E2 unconjugated Recombinant Antibody
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Sheep, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 Reactivity: Human, Rat WB, IHC, IF, ICC, FACS Host: Rabbit Polyclonal unconjugated
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Application Notes
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Expiry Date
- 12 months
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FOXO3
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Background
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Background: Forkhead box O3, also known as FKHRL1 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
Gene Full Name: forkhead box O3
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Gene ID
- 2309
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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