IFNAR2 antibody (AA 33-466) (Biotin)

Catalog No. ABIN8000946

The Rabbit Polyclonal anti-IFNAR2 antibody is suitable to detect IFNAR2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for IFNAR2 antibody (AA 33-466) (Biotin) (ABIN8000946)

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IFNAR2 Antibody (Biotin)

Binding Specificity: AA 33-466

Purpose: Anti-IFNAR2 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IFNAR2 recombinant protein (Position: D33-Q466).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Alternative Name: IFNAR2

Background:

Background: Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene. It is mapped to 21q22.11. The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Gene Full Name: interferon alpha and beta receptor subunit 2

Gene ID: 3455

UniProt: P48551

Pathways: JAK-STAT Signaling, Hepatitis C