CYP24A1 antibody (AA 351-450) (Cy3)
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- Target See all CYP24A1 Antibodies
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
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Binding Specificity
- AA 351-450
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP24A1 antibody is conjugated to Cy3
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CYP24A1
- Isotype
- IgG
- Top Product
- Discover our top product CYP24A1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- Alternative Name
- CYP24A1 (CYP24A1 Products)
- Synonyms
- CP24 antibody, CYP24 antibody, HCAI antibody, P450-CC24 antibody, 24-OHase antibody, Cyp24 antibody, 25-hydroxyvitaminD324-hydroxylase antibody, VITD12 antibody, CP450CC24 antibody, cytochrome P450 family 24 subfamily A member 1 antibody, cytochrome P450, family 24, subfamily a, polypeptide 1 antibody, cytochrome P450, family 24, subfamily A, polypeptide 1 antibody, CYP24A1 antibody, Cyp24a1 antibody
- Background
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Synonyms: CP24, HCAI, CYP24, P450-CC24, 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1
Background: Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
- Gene ID
- 1591
- UniProt
- Q07973
- Pathways
- Metabolism of Steroid Hormones and Vitamin D
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