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CYP24A1 antibody (AA 351-450) (Cy3)

CYP24A1 Reactivity: Human, Mouse IF (cc), IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN750841
  • Target See all CYP24A1 Antibodies
    CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
    Binding Specificity
    • 14
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 42
    • 24
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 39
    • 3
    • 1
    Rabbit
    Clonality
    • 41
    • 2
    Polyclonal
    Conjugate
    • 30
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP24A1 antibody is conjugated to Cy3
    Application
    • 29
    • 14
    • 12
    • 12
    • 11
    • 9
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CYP24A1
    Isotype
    IgG
    Top Product
    Discover our top product CYP24A1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
    Alternative Name
    CYP24A1 (CYP24A1 Products)
    Synonyms
    CP24 antibody, CYP24 antibody, HCAI antibody, P450-CC24 antibody, 24-OHase antibody, Cyp24 antibody, 25-hydroxyvitaminD324-hydroxylase antibody, VITD12 antibody, CP450CC24 antibody, cytochrome P450 family 24 subfamily A member 1 antibody, cytochrome P450, family 24, subfamily a, polypeptide 1 antibody, cytochrome P450, family 24, subfamily A, polypeptide 1 antibody, CYP24A1 antibody, Cyp24a1 antibody
    Background

    Synonyms: CP24, HCAI, CYP24, P450-CC24, 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1

    Background: Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.

    Gene ID
    1591
    UniProt
    Q07973
    Pathways
    Metabolism of Steroid Hormones and Vitamin D
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