HNF4A antibody (pSer313)

Catalog No. ABIN752353

Product Details anti-HNF4A Antibody

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Binding Specificity: pSer313

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HNF4 alpha around the phosphorylation site of Ser313

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HNF4A

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Alternative Name: HNF4 (HNF4A Products)

Synonyms: HNF4A antibody, HNF4alpha antibody, CG9310 antibody, DmHNF4 antibody, Dmel\\CG9310 antibody, HNF-4 antibody, HNF-4(D) antibody, HNF4 antibody, Hnf-4 antibody, Hnf-4h antibody, NR2A4 antibody, dHNF-4 antibody, dHNF4 antibody, Hnf4 antibody, Hnf4alpha antibody, MODY1 antibody, Nr2a1 antibody, Tcf14 antibody, HNF4a7 antibody, HNF4a8 antibody, HNF4a9 antibody, MODY antibody, NR2A1 antibody, NR2A21 antibody, TCF antibody, TCF14 antibody, HNF-4alpha antibody, fb58h09 antibody, id:ibd1279 antibody, wu:fb58h09 antibody, hnf4 antibody, nr2a1 antibody, hepatocyte nuclear factor 4 alpha antibody, Hepatocyte nuclear factor 4 antibody, hepatic nuclear factor 4, alpha antibody, hepatocyte nuclear factor 4, alpha antibody, hepatocyte nuclear factor 4 alpha S homeolog antibody, HNF4A antibody, hnf4a antibody, Hnf4 antibody, Hnf4a antibody, hnf4a.S antibody

Background:

Synonyms: Hepatic nuclear factor 4 alpha, Hepatocyte nuclear factor 4 alpha, Hepatocyte nuclear factor 4, HNF 4 alpha, HNF 4, HNF4, HNF4A, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, MODY 1, MODY, MODY1, NR2A1, NR2A21, Nuclear receptor subfamily 2 group A member 1, TCF 14, TCF, TCF14, Tcf4, Transcription factor 14, hepatic nuclear factor, Transcription factor 14, Transcription factor HNF 4, Transcription factor HNF4.

Background: The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.

Gene ID: 3172

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process