Retinoblastoma 1 antibody (AA 40-921) (HRP)
Quick Overview for Retinoblastoma 1 antibody (AA 40-921) (HRP) (ABIN8031769)
Target
See all Retinoblastoma 1 (RB1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-921
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Purpose
- Anti-RB1 Antibody HRP Conjugated
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Predicted Reactivity
- Human RB1 shares 91.6%,90.7% amino acid (aa) sequence identity with mouse,rat RB1,respectively.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human RB1 recombinant protein (Position: E40-D921). Human RB1 shares 91.6% and 90.7% amino acid (aa) sequence identity with mouse and rat RB1, respectively.
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Isotype
- IgG
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anti-Retinoblastoma 1 (RB1) (pSer612) antibody
RB1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB7659 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 586-615) antibodyRB1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB7977 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 858-886), (C-Term) antibodyRB1 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB20715 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 745-928) antibodyRB1 Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 2A11D11 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reactivity: Human WB, IF, IP, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer788) antibodyRB1 Reactivity: Human IHC (p), DB Host: Rabbit Polyclonal RB7670 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer811) antibodyRB1 Reactivity: Human IF, IHC (p), DB Host: Rabbit Polyclonal RB7679 unconjugated
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Application Notes
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- Retinoblastoma 1 (RB1)
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Alternative Name
- RB1
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Background
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Background: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Gene Full Name: RB transcriptional corepressor 1
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Gene ID
- 5925
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UniProt
- P06400
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Pathways
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
Target
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