Synaptotagmin antibody (AA 165-260) (HRP)

Catalog No. ABIN754897

Product Details anti-Synaptotagmin Antibody (HRP)

Target: Synaptotagmin (SYT)

Binding Specificity: AA 165-260

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptotagmin antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody will cross-react with Synaptotagmin 2 and

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Synaptotagmin 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Synaptotagmin

Target: Synaptotagmin (SYT)

Alternative Name: Synaptotagmin (SYT Products)

Synonyms: Syti antibody, GB20036 antibody, DKFZP459P193 antibody, SYT1 antibody, SytI antibody, SyNapTotagmin antibody, synaptotagmin antibody, synaptotagmin 1 antibody, snt-5 antibody, snt-6 antibody, snt-3 antibody, Syt antibody, Syt1 antibody, SYT1 antibody

Background:

Synonyms: P65, SYT, SVP65, Synaptotagmin-1, Synaptotagmin I, SytI, SYT1

Background: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins, syntaxin and AP2.

Gene ID: 6857

UniProt: P21579