CHFR antibody

Catalog No. ABIN8120483

This Rabbit Polyclonal antibody specifically detects CHFR in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHFR antibody (ABIN8120483)

Target: CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHFR antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CHFR Antibody

Purpose: Chfr Antibody

Specificity: Chfr Polyclonal Antibody detects endogenous levels of Chfr protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Chfr.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHFR

Target: CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))

Alternative Name: Chfr

Background:

Synonyms: CHFR, RNF196, E3 ubiquitin-protein ligase CHFR, Checkpoint with forkhead and RING finger domains protein, RING finger protein 196

Background: This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014],

Gene Name: CHFR

Protein Name: E3 ubiquitin-protein ligase CHFR

Gene ID: 55743

UniProt: Q96EP1