DDR1 antibody (pTyr796)

Catalog No. ABIN8121011

This Rabbit Polyclonal antibody specifically detects DDR1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for DDR1 antibody (pTyr796) (ABIN8121011)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DDR1 Antibody

Binding Specificity: pTyr796

Purpose: DDR1 (Phospho Tyr796) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat DDR1 (Phospho Tyr796)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human DDR1 (Phospho Tyr796)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Alternative Name: DDR1

Background:

Synonyms: Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1, EC 2.7.10.1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, Mammary carcinoma kinase 10, MCK-10, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CD antigen CD167a)

Background: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates.,function:May be involved in cell-cell interactions and recognition.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed at low levels in most adult tissues and is highest in the brain and lung. Abundant in breast carcinoma cell lines.,

Gene Name: DDR1 CAK EDDR1 NEP NTRK4 PTK3A RTK6 TRKE

Protein Name: DDR1 (Phospho Tyr796)

Gene ID: 780

UniProt: Q08345

Pathways: RTK Signaling, Smooth Muscle Cell Migration