Neuregulin 4 antibody (AA 11-60)

Catalog No. ABIN8123278

The Rabbit Polyclonal anti-Neuregulin 4 antibody (ABIN8123278) specifically detects Neuregulin 4 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Neuregulin 4 antibody (AA 11-60) (ABIN8123278)

Target: Neuregulin 4 (NRG4)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Neuregulin 4 Antibody

Binding Specificity: AA 11-60

Purpose: NRG4 Antibody

Specificity: NRG4 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Neuregulin 4

Target: Neuregulin 4 (NRG4)

Alternative Name: NRG4

Background:

Background: The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR, MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008],

Gene Name: NRG4

Protein Name: Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Cleaved into: Neuregulin-4 (NRG-4)]

Gene ID: 145957

UniProt: Q8WWG1

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway