Caspase 8 antibody

Catalog No. ABIN781444

This Mouse Monoclonal antibody specifically detects Caspase 8 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (ABIN781444)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Caspase 8 Antibody

Specificity: Cytoplasm

Purification: Protein G-Sepharose affinity purified.

Immunogen: A Synthetic peptide of human CASP8 (C-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100 - 1/2000.

Comment:

GeneBank ID: NM_001080125.1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Buffer: Preservative: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades