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CD11c antibody (AA 1155-1159)
ITGAX
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CD11c Antibody
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Target
See all CD11c (ITGAX) Antibodies
CD11c (ITGAX)
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Binding Specificity
All epitopes for CD11c antibodies
AA 1155-1159
Reactivity
All reactivities for CD11c antibodies
Human
Host
All hosts for CD11c antibodies
Rabbit
Clonality
All clonalities for CD11c antibodies
Polyclonal
Conjugate
All conjugates for CD11c antibodies
This CD11c antibody is un-conjugated
Application
All applications for CD11c antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous level of total CD11c protein.
Purification
Affinity purified
Immunogen
Peptide sequence around AA 1155-1159 (Q-T-P-S-P) derived from Human CD11c. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for CD11c
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Target
CD11c (ITGAX)
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Alternative Name
CD11c (ITGAX Products )
Synonyms
CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
Background
Integrin a-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Molecular Weight
145 kDa
Gene ID
3687
NCBI Accession
NP_000878
UniProt
P20702
Pathways
Complement System , Activated T Cell Proliferation , Integrin Complex
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