SYK antibody (pTyr323) (AbBy Fluor® 350)
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- Target See all SYK Antibodies
- SYK (Spleen tyrosine Kinase (SYK))
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Binding Specificity
- pTyr323
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SYK antibody is conjugated to AbBy Fluor® 350
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Cow
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr323
- Isotype
- IgG
- Top Product
- Discover our top product SYK Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SYK (Spleen tyrosine Kinase (SYK))
- Alternative Name
- Syk (SYK Products)
- Synonyms
- p72-Syk antibody, Sykb antibody, p72syk antibody, spleen associated tyrosine kinase antibody, spleen tyrosine kinase antibody, syk antibody, SYK antibody, Syk antibody
- Background
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Synonyms: syk Tyr323, Tyrosine-protein kinase SYK Spleen tyrosine kinase [Contains: 72 kDa tyrosine-protein kinase SYK, 40 kDa tyrosine-protein kinase SYK, KSYK_HUMAN.
Background: Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk, Spleen tyrosine kinase, Tyrosine protein kinase SYK.
- Gene ID
- 6850
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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