Angiotensin II Type-1 Receptor antibody (AA 201-300) (AbBy Fluor® 647)
-
- Target See all Angiotensin II Type-1 Receptor (AGTR1) Antibodies
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
-
Binding Specificity
- AA 201-300
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Angiotensin II Type-1 Receptor antibody is conjugated to AbBy Fluor® 647
-
Application
- Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human AT1R
- Isotype
- IgG
- Top Product
- Discover our top product AGTR1 Primary Antibody
-
-
- Application Notes
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
- Alternative Name
- Angiotensin II Type 1 Receptor (AGTR1 Products)
- Synonyms
- AG2S antibody, AGTR1A antibody, AGTR1B antibody, AT1 antibody, AT1AR antibody, AT1B antibody, AT1BR antibody, AT1R antibody, AT2R1 antibody, AT2R1A antibody, AT2R1B antibody, HAT1R antibody, 1810074K20Rik antibody, AI551199 antibody, AT1a antibody, Agtr-1a antibody, Agtr1 antibody, Angtr-1a antibody, AT1A antibody, XAT-1 antibody, agtr1-A antibody, agtr1.2 antibody, AT1-R antibody, at1 antibody, AGTR1 antibody, Agtr-1b antibody, Angtr-1b antibody, agtr1 antibody, agtr1-a antibody, agtr1-b antibody, xAT antibody, angiotensin II receptor type 1 antibody, angiotensin II receptor, type 1a antibody, angiotensin II receptor type 1 S homeolog antibody, uncharacterized AGTR1 antibody, angiotensin II receptor, type 1b antibody, angiotensin II receptor type 1 L homeolog antibody, AGTR1 antibody, Agtr1a antibody, agtr1.S antibody, Agtr1 antibody, Agtr1b antibody, agtr1.L antibody
- Background
-
Synonyms: AG2S, Agtr 1, Agtr1, Agtr1a, AGTR1B, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, AT-1B, AT-1r, AT1, At1a, AT1AR, AT1B, AT1BR, AT2R1, AT2R1A, AT2R1B, HAT1R, Type 1 angiotensin II receptor, AGTR1_HUMAN, Type-1 angiotensin II receptor, Angiotensin II type-1 receptor, AT1R, Ang II, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, Angiotensin receptor 1, Angiotensin receptor 1B, AT 1B, AT1, AT1R.
Background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].
- Gene ID
- 185
- UniProt
- P30556
- Pathways
- JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
-