DUSP7 antibody (AA 321-419) (Alexa Fluor 488)

Catalog No. ABIN894603

Product Details anti-DUSP7 Antibody (Alexa Fluor 488)

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Binding Specificity: AA 321-419

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP7 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUSP7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DUSP7

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Alternative Name: DUSP7 (DUSP7 Products)

Synonyms: DUSP7 antibody, mkpx antibody, mkp-x antibody, pyst2 antibody, MKPX antibody, PYST2 antibody, AU015694 antibody, Mkpx antibody, Pyst2 antibody, mkp-X antibody, dual specificity phosphatase 7 antibody, Dual specificity protein phosphatase 7 antibody, DUSP7 antibody, dusp7 antibody, dus7 antibody, Dusp7 antibody

Background:

Synonyms: Dual specicity phosphatase 7, Dual specicity protein phosphatase 7, Dual specicity protein phosphatase PYST2, DUS7_HUMAN, Dusp7, Jnk Stimulatory Phosphatase 1, JSP1, MKPX, PYST2.

Background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses

Gene ID: 1849

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades