HCK antibody (AA 301-450) (Alexa Fluor 555)

Catalog No. ABIN900258

Product Details anti-HCK Antibody (Alexa Fluor 555)

Target: HCK (Hemopoietic Cell Kinase (HCK))

Binding Specificity: AA 301-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCK antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Hck

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Alternative Name: Hck (HCK Products)

Synonyms: laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody

Background:

Synonyms: Bmk, Hck 1, Hemopoietic cell kinase, Hemopoietic cell kinase isoform p59 Hck, JTK 9, JTK9, MGC 18625, MGC18625, p59 HCK/p60 HCK, p59HCK/p60HCK, Tyrosine protein kinase HCK.

Background: HCK is a tyrosine kinase that is predominantly expressed in hemopoietic cell types. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils.

Gene ID: 3055

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling