IGF2BP3 antibody (AA 101-230) (Alexa Fluor 350)
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- Target See all IGF2BP3 Antibodies
- IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
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Binding Specificity
- AA 101-230
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IGF2BP3 antibody is conjugated to Alexa Fluor 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Insulin-like growth factor 2 mRNA-binding protein 3
- Isotype
- IgG
- Top Product
- Discover our top product IGF2BP3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
- Alternative Name
- IGF2BP3 (IGF2BP3 Products)
- Synonyms
- CT98 antibody, IMP-3 antibody, IMP3 antibody, KOC1 antibody, VICKZ3 antibody, Ab2-255 antibody, RGD1306512 antibody, imp3 antibody, koc1 antibody, vera antibody, imp-3 antibody, vg1rbp antibody, vickz3 antibody, 2610101N11Rik antibody, AA522010 antibody, AL022933 antibody, AU045931 antibody, Koc13 antibody, Neilsen antibody, mimp3 antibody, dvr1rbp antibody, wu:fb79c12 antibody, wu:fe06h09 antibody, zVg1RBP antibody, B3 antibody, IGF2 mRNA-binding protein 3-B antibody, IMP antibody, IMP-3-B antibody, Vg1 RBP-B antibody, Vg1-RBP antibody, igf2bp3 antibody, igf2bp3-a antibody, igf2bp3-b antibody, IGF2 mRNA-binding protein 3-A antibody, IMP-3-A antibody, Vg1 RBP-A antibody, vera-A antibody, insulin like growth factor 2 mRNA binding protein 3 antibody, insulin-like growth factor 2 mRNA binding protein 3 antibody, insulin like growth factor 2 mRNA binding protein 3 S homeolog antibody, insulin like growth factor 2 mRNA binding protein 3 L homeolog antibody, IGF2BP3 antibody, Igf2bp3 antibody, igf2bp3 antibody, igf2bp3.S antibody, igf2bp3.L antibody
- Background
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Synonyms: KOC, CT98, IMP3, KOC1, IMP-3, VICKZ3, Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IGF-II mRNA-binding protein 3, KH domain-containing protein overexpressed in cancer, hKOC, VICKZ family member 3, IGF2BP3
Background: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.
- Gene ID
- 10643
- UniProt
- O00425
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