IL1RL1 antibody (PE-Cy3)

Catalog No. ABIN916596

Product Details anti-IL1RL1 Antibody (PE-Cy3)

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL1 antibody is conjugated to PE-Cy3

Application: Flow Cytometry (FACS)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Pig (Porcine), Dog (Canine), Cow (Bovine)

Purification: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogen: KLH conjugated synthetic peptide derived from human Interleukin 1 receptor like 1

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IL1RL1

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Alternative Name: ST2 (IL1RL1 Products)

Synonyms: DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, FIT-1 antibody, IL33R antibody, ST2 antibody, ST2V antibody, FIT1 antibody, interleukin 1 receptor-like 1 antibody, interleukin 1 receptor like 1 antibody, Il1rl1 antibody, IL1RL1 antibody

Background: ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.
Synonym: DER-4, DER4, homolog of mouse growth stimulation-expressed, Il1rl1, Interleukin 1 receptor like 1, interleukin 1 receptor related protein, Ly84, Lymphocyte antigen 84, ST2, ST2L, ST2V, Ste2, Suppressor of tumorigenicity 2, T1 protein.

Molecular Weight: 40kDa

Gene ID: 9173