HVEM antibody (Middle Region)

Catalog No. ABIN926735

Product Details anti-HVEM Antibody

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HVEM antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: TNFRSF14 antibody was raised in rabbit using the middle region of TNFRSF14 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

TNFRSF14 Blocking Peptide, catalog no. 33R-10421, is also available for use as a blocking control in assays to test for specificity of this TNFRSF14 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Alternative Name: TNFRSF14 (TNFRSF14 Products)

Synonyms: ATAR antibody, CD270 antibody, HVEA antibody, HVEM antibody, LIGHTR antibody, TR2 antibody, Atar antibody, HveA antibody, Hvem antibody, Tnfrs14 antibody, TNF receptor superfamily member 14 antibody, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) antibody, Tnfrsf14 antibody, TNFRSF14 antibody

Target Type: Viral Protein

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Synonyms: Polyclonal TNFRSF14 antibody, Anti-TNFRSF14 antibody, tumor necrosis factor receptor superfamily, member 14, herpesvirus entry mediator antibody, ATAR antibody, HVEA antibody, HVEM antibody, LIGHTR antibody, TR2 antibody.

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints