DcR1 antibody (N-Term)
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- Target See all DcR1 (TNFRSF10C) Antibodies
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DcR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- TNFRSF10 C antibody was raised in rabbit using the N terminal of TNFRSF10 as the immunogen
- Top Product
- Discover our top product TNFRSF10C Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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TNFRSF10C Blocking Peptide, catalog no. 33R-5730, is also available for use as a blocking control in assays to test for specificity of this TNFRSF10C antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- Alternative Name
- TNFRSF10C (TNFRSF10C Products)
- Synonyms
- CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
- Background
- TNFRSF10C is the receptor for the cytotoxic ligand TRAIL. TNFRSF10C lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. TNFRSF10C may protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. Synonyms: Polyclonal TNFRSF10C antibody, Anti-TNFRSF10C antibody, tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain antibody, CD263 antibody, DCR1 antibody, LIT antibody, MGC149501 antibody, MGC149502 antibody, TRAILR3 antibody, TRID antibody.
- Pathways
- Apoptosis
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