SMARCB1 antibody (Middle Region)

Catalog No. ABIN927476

Product Details anti-SMARCB1 Antibody

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Chicken, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCB1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Frog, Cow (Bovine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: SMARCB1 antibody was raised in rabbit using the middle region of SMARCB1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SMARCB1 Blocking Peptide, catalog no. 33R-4039, is also available for use as a blocking control in assays to test for specificity of this SMARCB1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SMARCB1

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Alternative Name: SMARCB1 (SMARCB1 Products)

Synonyms: SMARCB1 antibody, BAF47 antibody, INI1 antibody, MRD15 antibody, RDT antibody, RTPS1 antibody, SNF5 antibody, SNF5L1 antibody, Sfh1p antibody, Snr1 antibody, hSNFS antibody, AU020204 antibody, Baf47 antibody, Ini1 antibody, SNF5/INI1 antibody, Snf5 antibody, fc51b01 antibody, smarcb1 antibody, wu:fc51b01 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b antibody, SMARCB1 antibody, Smarcb1 antibody, smarcb1.S antibody, smarcb1b antibody

Background: The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Synonyms: Polyclonal SMARCB1 antibody, Anti-SMARCB1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 antibody.