Deltex Homolog 3 antibody (C-Term)

Catalog No. ABIN928019

Product Details anti-Deltex Homolog 3 Antibody

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deltex Homolog 3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Dtx3 antibody was raised in rabbit using the C terminal of Dtx3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Dtx3 Blocking Peptide, catalog no. 33R-10086, is also available for use as a blocking control in assays to test for specificity of this Dtx3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Deltex Homolog 3

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Alternative Name: Dtx3 (DTX3 Products)

Synonyms: RGD1566181 antibody, Deltex3 antibody, mg310 antibody, RNF154 antibody, deltex E3 ubiquitin ligase 3 antibody, deltex homolog 3 (Drosophila) antibody, deltex 3, E3 ubiquitin ligase antibody, Dtx3 antibody, DTX3 antibody, dtx3 antibody

Background: Dtx3 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Dtx3 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Dtx3 functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. Synonyms: Polyclonal Dtx3 antibody, Anti-Dtx3 antibody, deltex 3 homolog, Drosophila antibody, Deltex3 antibody, MGC106339 antibody, mg310 antibody.

Pathways: Notch Signaling