14-3-3 sigma/SFN antibody (N-Term)

Catalog No. ABIN928745

Product Details anti-14-3-3 sigma/SFN Antibody

Target: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 sigma/SFN antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: SFN antibody was raised in rabbit using the N terminal of SFN as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SFN Blocking Peptide, catalog no. 33R-9879, is also available for use as a blocking control in assays to test for specificity of this SFN antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for 14-3-3 sigma/SFN

Target: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Alternative Name: SFN (SFN Products)

Synonyms: YWHAS antibody, Er antibody, Mme1 antibody, Ywhas antibody, stratifin antibody, SFN antibody, Sfn antibody

Background: SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. Synonyms: Polyclonal SFN antibody, Anti-SFN antibody, stratifin antibody, YWHAS antibody.

Pathways: p53 Signaling, Myometrial Relaxation and Contraction