LIG3 antibody (Middle Region)

Catalog No. ABIN928753

Product Details anti-LIG3 Antibody

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Binding Specificity: Middle Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Lig3 antibody was raised in rabbit using the middle region of Lig3 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Lig3 Blocking Peptide, catalog no. 33R-9302, is also available for use as a blocking control in assays to test for specificity of this Lig3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: Lig3 (LIG3 Products)

Synonyms: orf36 antibody, DDBDRAFT_0218523 antibody, DDBDRAFT_0232266 antibody, DDB_0218523 antibody, DDB_0232266 antibody, LIG3 antibody, wu:fb12c02 antibody, wu:fd10b03 antibody, wu:fm79b09 antibody, LIG2 antibody, D11Wsu78e antibody, An02g06890 antibody, AO090003000668 antibody, lig3 antibody, DNA ligase III antibody, BRCT domain-containing protein antibody, DNA ligase 3 antibody, ligase III, DNA, ATP-dependent antibody, ligase III, DNA, ATP-dependent L homeolog antibody, orf36 antibody, lig3 antibody, LIG3 antibody, Lig3 antibody, Bm1_22840 antibody, ANI_1_2644024 antibody, AOR_1_1174154 antibody, LOC100634887 antibody, lig3.L antibody

Background: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining  of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in  excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream  start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon  allowing for transport to the nucleus. Synonyms: Polyclonal Lig3 antibody, Anti-Lig3 antibody, ligase III, DNA, ATP-dependent antibody, Lig3 antibody.

Pathways: DNA Damage Repair