EIF2C3 antibody (N-Term)

Catalog No. ABIN929063

Product Details anti-EIF2C3 Antibody

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2C3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Eif2 c3 antibody was raised in rabbit using the N terminal of Eif2 3 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Eif2c3 Blocking Peptide, catalog no. 33R-9576, is also available for use as a blocking control in assays to test for specificity of this Eif2c3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for EIF2C3

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Alternative Name: Eif2c3 (EIF2C3 Products)

Synonyms: EIF2C3 antibody, Eif2c3 antibody, Argonaute3 antibody, ago3 antibody, eif2c3 antibody, eif2c3b antibody, si:dkey-3n22.3 antibody, AW048688 antibody, C130014L07Rik antibody, ARGONAUTE 3 antibody, T19E23.8 antibody, T19E23_8 antibody, argonaute 3, RISC catalytic component antibody, argonaute RISC catalytic component 3b antibody, argonaute RISC catalytic subunit 3 antibody, argonaute RISC catalytic component 3 antibody, ARGONAUTE 3 antibody, AGO3 antibody, Ago3 antibody, ago3b antibody

Background: Eif2c3 is required for RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. It lacks endonuclease activity and does not appear to cleave target mRNAs. Synonyms: Polyclonal Eif2c3 antibody, Anti-Eif2c3 antibody, eukaryotic translation initiation factor 2C, 3 antibody, AW048688 antibody, Ago3 antibody, C130014L07Rik antibody.

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway