CD27 antibody (C-Term)

Catalog No. ABIN929125

Product Details anti-CD27 Antibody

Target: CD27 (CD27 Molecule (CD27))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD27 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CD27 antibody was raised in rabbit using the C terminal of CD27 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CD27 Blocking Peptide, catalog no. 33R-5024, is also available for use as a blocking control in assays to test for specificity of this CD27 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CD27

Target: CD27 (CD27 Molecule (CD27))

Alternative Name: CD27 (CD27 Products)

Synonyms: TNFRSF7 antibody, S152 antibody, Tnfrsf7 antibody, Tp55 antibody, S152. LPFS2 antibody, T14 antibody, CD27 molecule antibody, CD27 antigen antibody, CD27 antibody, Cd27 antibody

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. Synonyms: Polyclonal CD27 antibody, Anti-CD27 antibody, CD27 molecule antibody, MGC20393 antibody, S152 antibody, T14 antibody, TNFRSF7 antibody, Tp55 antibody.

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints