SRA1 antibody

Catalog No. ABIN931300

Product Details anti-SRA1 Antibody

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SRA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: SRA antibody was raised in Mouse using a purified recombinant fragment of SRA expressed in E. coli as the immunogen.

Clone: 7H1G1

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Alternative Name: SRA (SRA1 Products)

Synonyms: SRA antibody, SRAP antibody, STRAA1 antibody, pp7684 antibody, AA959952 antibody, Sra antibody, Srap antibody, Straa1 antibody, Strra1 antibody, zgc:86613 antibody, steroid receptor RNA activator 1 antibody, steroid receptor RNA activator 1 S homeolog antibody, cytoplasmic FMR1 interacting protein 1 antibody, SRA1 antibody, Sra1 antibody, sra1 antibody, sra1.S antibody, CYFIP1 antibody

Background: SRA belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis. Synonyms: Monoclonal SRA antibody, Anti-SRA antibody, Steroid receptor RNA activator 1 antibody, Steroid receptor RNA activator antibody.

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development