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IKK alpha antibody (AA 500-590)
CHUK
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
7C10B6-1A10A10
unconjugated
Product Details anti-IKK alpha Antibody
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Target
See all IKK alpha (CHUK) Antibodies
IKK alpha (CHUK)
(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
Binding Specificity
All epitopes for IKK alpha antibodies
AA 500-590
Reactivity
All reactivities for IKK alpha antibodies
Human
Host
All hosts for IKK alpha antibodies
Mouse
Clonality
All clonalities for IKK alpha antibodies
Monoclonal
Conjugate
All conjugates for IKK alpha antibodies
This IKK alpha antibody is un-conjugated
Application
All applications for IKK alpha antibodies
Western Blotting (WB), ELISA
Immunogen
CHUK antibody was raised in Mouse using a purified recombinant fragment of CHUK(aa500-590) expressed in E. coli as the immunogen.
Clone
7C10B6-1A10A10
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for IKK alpha
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Target
IKK alpha (CHUK)
(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
Alternative Name
CHUK (CHUK Products )
Background
CHUK is a member of the serine/threonine protein kinase family, CHUK is a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. Synonyms: Monoclonal CHUK antibody, Anti-CHUK antibody, Conserved helix-loop-helix ubiquitous kinase antibody.
Pathways
PI3K-Akt Signaling , NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
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