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SLC9A3R1 antibody
SLC9A3R1
Reactivity: Human
WB, IP, IHC (p)
Host: Mouse
Monoclonal
EBP-10
unconjugated
Product Details anti-SLC9A3R1 Antibody
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Target
See all SLC9A3R1 Antibodies
SLC9A3R1
(Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))
Reactivity
All reactivities for SLC9A3R1 antibodies
Human
Host
All hosts for SLC9A3R1 antibodies
Mouse
Clonality
All clonalities for SLC9A3R1 antibodies
Monoclonal
Conjugate
All conjugates for SLC9A3R1 antibodies
This SLC9A3R1 antibody is un-conjugated
Application
All applications for SLC9A3R1 antibodies
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
The mouse monoclonal antibody EBP-10 reacts with NHERF1/EBP50 phosphoprotein of 50 kDa, which serves as an adaptor and regulator protein.
Cross-Reactivity (Details)
Other not tested, Human
Purification
Purified by protein-A affinity chromatography.
Purity
> 95 % (by SDS-PAGE)
Immunogen
Bacterially produced recombinant full-length human NHERF1.
Clone
EBP-10
Isotype
IgG1 kappa
Top Product
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Alternatives
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Application Details
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Application Notes
Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL. Western blotting: Recommended dilution: 2 μg/mL, reducing conditions, positive control: MCF-7 cell line
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Do not freeze.
Storage
4 °C
Storage Comment
Store at 2-8°C. Do not freeze.
Target Details for SLC9A3R1
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Target
SLC9A3R1
(Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))
Alternative Name
NHERF1 / EBP50 (SLC9A3R1 Products )
Synonyms
EBP50 antibody, NHERF antibody, NHERF-1 antibody, NHERF1 antibody, NPHLOP2 antibody, SLC9A3R1 antibody, cb895 antibody, slc9a3r2 antibody, wu:fd20a02 antibody, zgc:55541 antibody, zgc:77629 antibody, EBP-50 antibody, NHE-RF antibody, nherf antibody, nherf-1 antibody, nherf1 antibody, slc9a3r1 antibody, SLC9A3 regulator 1 antibody, microRNA 3615 antibody, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a antibody, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 antibody, SLC9A3 regulator 1 S homeolog antibody, SLC9A3R1 antibody, MIR3615 antibody, slc9a3r1a antibody, Slc9a3r1 antibody, slc9a3r1.S antibody
Background
SLC9A3 regulator 1,NHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50) is an adaptor protein, which associates with beta-catenin and is required for its localization at the cell-cell junctions, interacts with various G protein-coupled receptors and regulates their traffic, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate its interactions.,EBP50, NPHLOP2, SLC9A3R1, SR1
Gene ID
9368
UniProt
O14745
Pathways
Proton Transport , Platelet-derived growth Factor Receptor Signaling , Negative Regulation of Transporter Activity , SARS-CoV-2 Protein Interactome
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