CPS1 antibody (N-Term)

Catalog No. ABIN951681

Product Details anti-CPS1 Antibody

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Binding Specificity: AA 261-291, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPS1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human CPS1 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 261-291 amino acids from the N-terminal region of Human CPS1 Genename: CPS1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CPS1

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Alternative Name: CPS1 (CPS1 Products)

Synonyms: CPSASE1 antibody, cps antibody, 4732433M03Rik antibody, CPS antibody, D1Ucla3 antibody, Cps1 antibody, carbamoyl-phosphate synthase 1 antibody, carbamoyl-phosphate synthase 1 L homeolog antibody, carbamoyl-phosphate synthetase 1 antibody, peptidase M20 domain containing 1 antibody, CPS1 antibody, Cps1 antibody, cps1.L antibody, cps1 antibody, PM20D1 antibody

Background: The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.Synonyms: CPSase I, Carbamoyl-phosphate synthetase I, mitochondrial Carbamoyl-phosphate synthase

Molecular Weight: 164939 Da

Gene ID: 1373

NCBI Accession: NP_001116105

Pathways: Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process