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HECW2 antibody (Middle Region)
HECW2
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HECW2 Antibody
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Target
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HECW2
(HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2))
Binding Specificity
All epitopes for HECW2 antibodies
AA 847-876, Middle Region
Reactivity
All reactivities for HECW2 antibodies
Human, Mouse
Host
All hosts for HECW2 antibodies
Rabbit
Clonality
All clonalities for HECW2 antibodies
Polyclonal
Conjugate
All conjugates for HECW2 antibodies
This HECW2 antibody is un-conjugated
Application
All applications for HECW2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human and Mouse HECW2 (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human HECW2
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HECW2
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Target
HECW2
(HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2))
Alternative Name
NEDL2 (HECW2 Products )
Synonyms
HECW2 antibody, NEDL2 antibody, A730039N16Rik antibody, D030049F17Rik antibody, Gm971 antibody, Nedl2 antibody, mKIAA1301 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 antibody, E3 ubiquitin-protein ligase HECW2 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b antibody, Hecw2 antibody, HECW2 antibody, LOC531691 antibody, hecw2b antibody, hecw2 antibody
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.Synonyms: HECT, HECW2, KIAA1301, NEDD4-like E3 ubiquitin-protein ligase 2
Molecular Weight
175769 Da
Gene ID
57520
NCBI Accession
NP_065811
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