SERPINB8 antibody

Catalog No. ABIN954747

Product Details anti-SERPINB8 Antibody

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SERPINB8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific for Human Proteinase Inhibitor 8 (PI8).

Purification: Affinity chromatography on Protein G

Immunogen: Human Proteinase Inhibitor 8 (PI8) purified from the supernatant of thrombin activated platelets.

Clone: Anti-PI8K

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SERPINB8

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Alternative Name: SERPINB8 (SERPINB8 Products)

Synonyms: pi8 antibody, cap2 antibody, CAP-2 antibody, CAP2 antibody, NK10 antibody, Spi8 antibody, ovalbumin antibody, PI8 antibody, serpin family B member 8 antibody, serpin B8 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 8 antibody, Serpinb8 antibody, SERPINB8 antibody, LOC607205 antibody, serpinb8 antibody, LOC100424017 antibody

Background: Serpins are a group of proteins with similar structures that have been shown to inhibit proteases. Many serpins, like PI8 inhibit chymotrypsin - like serine proteases (serine protease inhibitors). Human proteinase inhibitor 8 (PI8) is a widely expressed 45- kDa ovalbumin type serpin. PI8 forms a complex with Furin, a ubiquitous mammalian endoproteinase in order to inhibit it. PI8 is also a potent inhibitor of bacillus subtilis, a Gram and catalase positive bacteria commonly found in soil.Synonyms: CAP-2, CAP2, Cytoplasmic antiproteinase 2, PI-8, PI8, Peptidase inhibitor 8, Serpin B8, clade B (ovalbumin) member 8, serpin peptidase inhibitor

Gene ID: 5271

NCBI Accession: NP_002631

UniProt: P50452