CDK5 antibody (Cyclin-Dependent Kinase 5)

Details for Product anti-CDK5 Antibody No. ABIN965844
Antigen
  • PSSALRE
  • AW048668
  • Crk6
  • CDK5
  • CG8203
  • DmCdk5
  • Dmel\\CG8203
  • cdk5
  • zgc:101604
  • cyclin dependent kinase 5
  • cyclin-dependent kinase 5
  • Cyclin-dependent kinase 5
  • cyclin-dependent kinase 5 L homeolog
  • Cyclin-dependent-like kinase 5
  • CDK5
  • Cdk5
  • cdk5
  • cdk5.L
  • cdk-5
Reactivity
Human, Monkey, Rat (Rattus)
268
175
169
19
18
17
16
15
13
13
10
9
5
5
3
3
3
2
1
1
1
Host
Mouse
206
71
Clonality (Clone)
Monoclonal ()
Conjugate
This CDK5 antibody is un-conjugated
12
7
6
6
6
6
6
6
5
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
214
101
58
42
34
32
27
18
17
12
5
3
3
Options
Immunogen Purified recombinant fragment of human CDK5 expressed in E. Coli.
Clone 4E4
Isotype IgG1
Purification Ascitic fluid
Plasmids, Primers & others Plasmids, Primers & others CDK5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CDK5 (CDK5 Antibody Abstract)
Background Function: Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
Synonyms: PSSALRE
Molecular Weight 35kDa
Gene ID 1020
Pathways Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Choi, Lee, Park, Sung, Lee, Shin, Ryu, Kim: "Single-nucleotide polymorphisms in the promoter of the CDK5 gene and lung cancer risk in a Korean population." in: Journal of human genetics, Vol. 54, Issue 5, pp. 298-303, 2009 (PubMed).

Zhang, Herrup: "Cdk5 and the non-catalytic arrest of the neuronal cell cycle." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3487-90, 2008 (PubMed).

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